Chemist I - Indianapolis, IN

Position Title: Analyst I

Hours Worked: Monday through Friday, forty-hours per week. However, must be flexible to meet the needs of the department and complete other projects as assigned.

Position Summary:

The Chemist I is responsible for the downstream processing of oligo synthesis using various analytical techniques.  AKTA, LC-MS, UPLC, LTQ, QDA analytical instruments are used.

Duties and Responsibilities:

• Downstream processing of oligo synthesis: cleavage, deprotection, purification and desalt methods. 
• Bioconjugation of single strand oligonucleotides
• Work closely with members of the RNAi chemistry team to understand and validate requirements for the downstream processing
• Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances
• Instrumentation for methods and techniques described include AKTA, LC-MS, UPLC, LTQ, QDA, Nanodrop, etc.
• Data analysis and troubleshooting
• Lab experience with solution preparation, separation, quantification of DNA/RNA, oligonucleotides, etc.
• Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.
• Detailed record keeping of daily experiments in ELNs (electronic laboratory notebooks)
• General Lab Maintenance
• Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.
• Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.
• Perform other essential tasks projects and responsibilities as required.
• Other duties as defined by Manager, department needs and workload

Skills & Proficiencies:

• Strong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water’s QDA, etc.
• Experience in developing new chromatographic methods (IEX/RP-HPLC, SPE, LC-MS)
• Strong organizational skills
• Strong written and oral communication skills
• Confident, execution-focused, and team oriented with a desire to thrive in a fast-paced growing environment
• Written and verbal communication skills including the ability to communicate effectively in a group setting, with colleagues and clients
• Ability to perform multiple tasks
• Ability to organize and prioritize workload to meet or exceed deadlines
• Individual and Team work ethic
• Proficiency with Windows, Word & Excel
• Attention to detail
• Positive attitude, self-motivated, high level of engagement
• Adheres to company values

Education and Experience:

• Degree requirement: Bachelor's Degree in Chemistry, Biochemistry, or closely related field
• Minimum of one (1) year of experience in a chemistry lab setting

An equivalent combination of education and experience may be accepted in lieu of above.